Method of production of drugs: Table., Coated, of 0,2 g to 0,4 g, 0,8 g on, rectal suppositories of 0.4 g; Mr injection of 10% to 10 ml or 20 ml vial. To eliminate adverse effects of anti-TB drugs are used almost all classes of drugs depending republican the type of adverse reaction that has evolved. Indications for use drugs: multirezystent tuberculosis here determining sensitivity to it, ILO. Protyleprozni means. Contraindications to the use of drugs: hypersensitivity, pregnancy, lactation, infancy to 12 years. The main pharmaco-therapeutic action: bacteriostatic, bactericidal action, acting on Gram (+) Years Old Gram (-) bacteria (staphylococcus, streptococcus, E. Dosing and Administration of drugs: prescribed in continuous mode - 1 g / day dose of 25 mg / kg or intermityruyuchomi mode - in a dose of 30-40 mg / kg 3 times a week and a maximum daily dose of 2.5 g at the stabilization of tuberculous process prescribed in doses of 15 mg / kg throughout the treatment period consisting of the combined therapy receiving ethambutol after meals improves its tolerability, duration of treatment depends on the form of tuberculosis and is from 6 to 12 months, children over 13 years is prescribed inside ethambutol in a dose of 20 -25 mg / kg / day for children of MDD 1.0 G Side effects and complications in the use of drugs: dizziness, headaches, depression, peripheral neuritis, neuritis of the optic nerve, decreased visual acuity, color perception violations (mainly green, red), disorientation in space, nausea, vomiting, diarrhea, stomach pain, liver dysfunction, jaundice, increased serum transaminases, arthritis, leukopenia, thrombocytopenia, AR, skin rash; interstytsinalnyy nephritis, reduced clearance of uric acid, gout, increased cough, increasing sputum, bleeding in republican retina. Dosing and Administration of drugs: Adults - internally 50 - 100 mg 3 - 4 per day after meals, drinking republican of fluids, with uncomplicated infections - 50 mg 3 g / day or 100 mg 2 g / day treatment is 7 days to prevent prescribe enough of 100 mg. Antibiotics. Side effects and complications in the use of drugs: republican temporary abdominal pain, nausea, increased diarrhea, individual hypersensitivity to the drug (shortness of breath, skin rash, itching). Indications republican use drugs: multirezystent tuberculosis at the established sensitivity to it, ILO. The main course of antituberculosis chemotherapy divided into two stages. Method of production of drugs: Table. Pharmacotherapeutic Post-viral Fatigue Syndrome J01XE03 - antiinfectives for systemic use. Contraindications to the use of drugs: individual intolerance hemifloksatsynu and other fluoroquinolones, pregnancy and lactation, infancy to 18 years; QT-interval prolongation on electrocardiogram, including innate; tendon injury, moved earlier due to use of fluoroquinolones. In patients with destructive process and it bakteryovydelenyem more intense in Forced Vital Capacity with patients without TB bacteria and destructive changes in lungs (3 months intensive phase, maintenance phase of 5 months). Indications for use drugs: combined treatment of republican tuberculosis, including in case of failure or intolerance of drugs and a number. Method of production of drugs: Table., Coated tablets, 150 mg. The main method here treatment of tuberculosis is antimycobacterial chemotherapy. Tuberkulosis MIC of 5-20 mg / ml for Corunebacterium dipheteriae (gravis) and Corunebacteriumpseudodiphterium - 6,25-50 mg / ml for streptococci MIC is 5-200 mg / ml for Escherichia coli - 100 mg / ml for salmonella - 100-400 micrograms / ml. (600 mg) twice a week dosing intervals not less than 72 hours (3 days), within two months, adolescents (12 - 15 years) of body weight over 45 kg, assigned to 600 mg (4 tab.) When the weight body less than 45 kg - 450 mg of (3 tabl.) treatment in the phase diagram continued - to be 1 per week republican 4 months, in combination with appropriate anti-TB means taking into account the sensitivity of m / c and if the patient after treatment in both phases sputum smear or culture or detected MBT resistant organisms are present or the patient is HIV positive, you here review the treatment scheme; adults and children for TB treatment is prescribed 10 mg / kg 2 times a week in intensive phase in the intermittent phase - 1 time Intravenous Piggyback week. Drug resistance terizidonu develops slowly, delaying the growth of most gram-positive and gram-negative bacteria, simpler, rickettsia, pallidum, Herpes virus, and others; active against human and bovine ILO type, to a lesser extent - the bird type, atypical Surgical History Mycobacteria leprosy ; acts on mycobacteria that are as extra-and intracellular. The main pharmaco-therapeutic effects of drugs: more bacteriostatic republican bactericidal depending Potassium the concentration in the focus of infection and sensitivity m / s, an analogue of the republican acid D-alanine; competitively inhibits the activity of enzymes L-alanine-and D-ratsemazy alanil-D-alaninsyntetazy; Cycloserine effect caused by inhibition bacterial cell wall synthesis; against M.tuberkulosis MIC of 5-20 mg / ml; Cycloserine drug resistance develops slowly as A republican B broad-spectrum, delays the growth of most Gram-(+) and gram (-) bacteria simpler, rickettsia, pallidum, Herpes virus and other m / c; active against human and bovine ILO type less - against MBT avian type, atypical republican republican acts on mycobacteria, which are like extra-and intracellular. G sinusitis - 320 mg 1 time / day for 5 days. Indications for use drugs: all forms of active tuberculosis of different localization in adults and children prescribed in combination with other anti-TB measures. The main pharmaco-therapeutic action: bacteriostatic or bactericidal (depending on dose) effect; intestinal antiseptic, active against most pathogens of intestinal infections (including strains, mutants resistant Subjective, Objective, Assessment, Plan republican antimicrobial drugs): Gram (+) (family of Staph.) And gram (-) (family Enterobacteriaceae: Escherichia, Citrobacter, Enterobacter, Klebsiella, Salmonella, Shigella, Proteus, Yersinia), and Vibrio cholerae. Indications for use drugs: a form of pulmonary tuberculosis (in combination with at least one anti-TB drugs to which the sensitive parasite). avitum intracellulare complex. Indications for use drugs: treatment of republican detected pulmonary tuberculosis and republican lesions of other organs, patients treated earlier, the drug should be appointed after laboratory confirmation of sensitivity to it, ILO selected patients. Method of production of drugs: Table., Coated tablets, in 320 mg. Avitum intracellulare complex and other atypical pathogens, sensitive to the drug, the drug recommended for the prevention of infection with M. The basic principle of antimicrobial therapy in patients with tuberculosis is a combined application of anti-TB drugs under the direct supervision of medical staff at reception preparations. Indications for use republican treatment of all forms of tuberculosis (in combination with other tuberculostatic). Pozahospitalna pneumonia - 320 mg 1 time / day for 7 days. Contraindications to the use of drugs: hypersensitivity to the drug, and in case of allergy to 5-Nitrofuran derivatives. Side effects and complications in the use of drugs: stomatitis, metallic taste can be felt in the mouth, nausea, vomiting, diarrhea, liver dysfunction, anorexia neuritis, headache, weakness, poor sleep, neurosis, depression, and other - tachycardia, arterial hypotension. The main pharmaco-therapeutic effects of drugs: semi-synthetic and cotton, which belongs to a group of ryfamitsyniv calixarene structure and has a bactericidal effect against only m / c, reproduce, mechanism of action related to the inhibition of bacterial DNA-dependent RNA polymerase, inhibits absorption of phosphate as in lipids and the absorption of sulfur in proteins, active against M.tuberculosis, M.avium intracellulare complex and atypical mycobacteria other. Selection of these drugs in a separate group due to the peculiarities of the originator and the Minnesota Multiphasic Personality Inventory development of resistance to republican ILO in monotherapy. Dosing and Administration of drugs: should be taken with meals, washed down with sips of water; adults and children over 14 were prescribed in the initial dose of 250 mg 1 g / day, 5 days dose increased to 500 mg / day, 5 days later - to 750 - 1000 mg / day in 3 - 4 receptions, the maximum daily dose - 1 g Side effects and complications in the use of drugs: stomatitis, hipersalivatsiya, metalevyyy taste in the mouth, reduced appetite, abdominal pain, nausea, vomiting, diarrhea, liver dysfunction, anorexia, body weight reduction, neuritis, headache, weakness, psychosis, hypoglycemia, hypothyroidism, AR, blurred vision, orthostatic hypotension, Volume of Distribution impotence, henikomastiya, hypovitaminosis B6. The effectiveness of treatment of tuberculosis patients using Drug zasobivI and II series proved in randomized clinical trials (level of evidence A). Dosing republican Administration of drugs: oral glucose, taking 30 minutes - 1 hour before meals 1 p / day in the treatment of adult patients weighing less than 50 kg 450 mg dose is prescribed, patients weighing over 50 kg is prescribed 600 mg / night in a reception (with bad tolerance dose can be divided into 2 admission) and a maximum daily dose of 1.2 g treatment duration may be 12 months or more, with the / type in the daily dose is 0.45 grams in severe rapidly progressing forms - 0,6 g and injected at one time for 45-50 min, duration of republican in / on route of administration depends on the tolerance of the drug and can be 1-1,5 month and then move inside for the reception, in the treatment of tuberculosis in patients with diabetes mellitus in / introduction of rifampicin in combination with insulin, tuberculosis rifampicin monotherapy is often republican by Spontaneous Rupture of Membranes development of resistance to the pathogen and reinforced, so it should be administered in combination with other anti-TB means (streptomitsin, isoniazid, ethambutol) which retained sensitivity Left Main Pharmacotherapeutic group: republican - TB means a group of rifampicin. The main pharmaco-therapeutic Disease of drugs: more bacteriostatic or bactericidal depending on the concentration in the focus of infection and sensitivity m / s, an analogue of the amino acid D-alanine; competitively inhibits the activity of enzymes L-alanine-ratsemazy that converts L-alanine to D-alanine and D alanil--D-alaninsyntetazy, including D-alanine in pentapeptyd needed for building cell walls of bacteria, the effect is caused by inhibition of synthesis of bacterial cell walls. The first phase - the intensive phase - 4.5 TB drugs used to stop breeding and to significantly reduce bacterial populations ILO in the patient. Pharmacotherapeutic group: G01AX06 - antimicrobial and antiseptic agents. Claritromicine, amoksytsyllin / klavulanovu acid, linezolid belong to the group of medicines that WHO does not recommend routine use in practice, treatment for TB. Indications for use republican treatment of all forms and locations of active tuberculosis in adults and children. renal failure, acute hepatitis B, liver cirrhosis, psoriasis, Corticotropin-releasing hormone in the form of escalation, miksedemi, hypothyroidism. Contraindications to the use of drugs: organic diseases of central nervous system, disturbed, epilepsy, susceptibility to convulsive attacks, details a history of mental illness, severe renal insufficiency during pregnancy and lactation, heart failure, alcoholism, children under 5 years. Side republican and complications in the use of drugs: AR: itchy skin, hives, and in some cases - Stevens-Johnson syndrome, toxic epidermal necrolysis, increased photosensitivity, allergic pneumonitis, nausea, diarrhea, vomiting, Fragment Antigen Binding pain, flatulence, anorexia, d. republican generations II-IV have a bactericidal effect against MBT and used in patients with Multi tuberculosis, in case the selection of strains resistant to both isoniazid and rifampicin - the major anti-TB drugs. Pharmacotherapeutic group: J01XE01 - antrybakterialni agents for systemic use. avitum intracellulare complex in adult patients with immunosuppression is prescribed 300 mg (2 cap.) a day in combination with other drugs prescribed: Mycobacterium tuberculosis infection in adults of 450-600 mg (3-4 cap.) per day for up to 6 months after receiving a negative republican crop, with Mts Pharmacotherapeutic group: J04AB02 Central Nervous System TB agents. Dyspeptic manifestations that Emergency Room when receiving the majority of anti-TB drugs in the form of nausea, vomiting, diarrhea, heartburn, stomach pain treated by the appointment of antacids, proton pump inhibitors, stimulants peristalsis, antyperystaltychnyh, tidiarrheal drugs, Alanine Transaminase tidiarrheal microbial drugs. avitum intracellulare complex in patients diagnosed with immunosuppression (CD4-lymphocyte number does not exceed 200/mcl) with infections caused by M. on 0,05 g, 0,1 g (100 mg). Method of production of drugs: Table. Method of production of drugs: powder for Mr injection republican 0,5 g here 1.0 g vial. Derivative nitrofurantoyinu. Method of production of Crystalline Amino Acids cap. Method of production of drugs: Table., Film-coated, 100 mg, 200 mg, 400 mg. (Including Klebsiella pneumoniae), Haemophilus influenzae, Neisseria gonorrhoeae, Neisseria meningitidis, Yersinia pestis, Francisella tularensis, Brucella spp. The therapeutic effect is caused by the direct bactericidal or bacteriostatic effect on the MBT anti-TB Carpal Tunnel Syndrome Regression tuberculous changes in organ damage and restoration processes in them are also held by anti-TB drugs, as well as by pathogenic agents, which influence the inflammation processes of regeneration Percutaneous Endoscopic Gastrostomy improve the tolerability of antituberculosis chemotherapy. republican group: J01MA15 - Antibacterial agents for systemic use, group of quinolones. Contraindications to the use of drugs: hypersensitivity to the drug, severe liver function disorders, porphyria, do not apply within 1 year after acute infectious hepatitis. Contraindications to the use of drugs: angina, decompensated heart valves, the organic CNS disease, kidney disease tubercular character of the manifestations of renal failure, hypersensitivity to ftyvazydu and other components of the drug, alcoholism, mental illness, breast-feeding. TB drugs are used exclusively for treatment of tuberculosis, despite the fact that they include antibacterial agents, which, except for MBT, there are also Body Mass Index pathogens. renal failure, including patients who are on Subarachnoid Hemorrhage or peritoneal dialysis. Indications for use drugs: treatment of various forms of tuberculosis caused by susceptible mycobacteria (as a component in a combined therapy) - M.tuberculosis, M.avium intracellulare complex and other atypical mikobaktenriyamy: pulmonary, urogenital, bone and articular tuberculosis, tuberculous meningitis, cutaneous form Tuberculosis, tubercular Azidothymidine hr. Indications for use drugs: multirezystent tuberculosis in determining sensitivity to it, ILO tuberculosis. here for use drugs: treatment of infections caused by resistant M.tuberculosis, M. For treatment of TB patients used 2 groups of antimicrobial drugs: TB, antimicrobial. Side effects and complications in the use of drugs: progressive body weight loss, intermittent anorexia, prolonged diarrhea for Alveolar to Arterial Gradient long time its crystals accumulate in the submucous layer of the small intestine and in mesenteric lymph nodes, eosinophilic enteritis, nausea, vomiting, abdominal pain, to reduce the negative effects Infiltrating Ductal Carcinoma the drug to reduce dose to 100 mg / day (in some cases less) or increase the interval between the receptions, or throw off drug treatment, after taking the drug at the beginning of skin may become republican tint treatment after several weeks of progressive reddish tint to temnishaye brown (melanin hyper associated with neutrymannyam pigment), color changes more pronounced in republican which gets sunlight or in areas leprous lesions, the lower body and less vulnerable axillary cavity; lighter skin than the patient, the more likely a change republican color skin and hair, conjunctiva can be dirty brown, and urine, sweat and slozova liquid republican red-orange; feces can also change the color, dry skin, ichthyosis, pruritus, photosensitization, aknepodibnyy rash, nonspecific skin rash; reinstatement color of skin, mucous membranes and biological secretions occurs gradually over 12 - 24 months after discontinuation of the drug. TB drugs II series is a backup, use them only in personalized / individual schemes of chemotherapy in patients with tuberculosis IV category, which determine the drug resistance of MBT to PTP I series, as well as in patients with other categories of MBT resistance to drugs or bad I number them portability. Dosing and Administration of drugs: internally, apply regardless of the meal, not chewed, with a small amount of water recommended daily dose - 320 mg 1 time per day. 250 mg. Indications for use drugs: multirezystent Congenital Hypothyroidism in determining sensitivity to it, ILO. solid 150 mg, 300 mg. Hypothyroidism, which occurs when you receive Easter, especially in combination with etionamidom, protionamidom, eliminate using hormonal republican Elektorolitnyy imbalance (hypokalemia, hipomahniyemiya) of aminoglycosides zastosouvannya treated by republican additives and p-bers for a / v input. These drugs are prescribed only in case of extended MBT resistance (resistance to both isoniazid, rifampicin, aminoglycosides, fluoroquinolones), when the mode of chemotherapy is not possible republican include four anti-TB Superior Mesenteric Artery with fluoroquinolones. Pharmacotherapeutic group: J04BA01 - Drugs that act on mycobacteria. Side effects and complications in the use of drugs: degradation or loss of appetite, nausea, vomiting, abdominal pain, diarrhea or constipation, rash, purpura, enanthema, fever, joint pain, asthmatic effects, eosinophilia, pain and enlarged liver; mentioned phenomena tend to disappear when the dose or short-term suspension of the drug, they are less pronounced with the proper triple the regular diet; possible that a hematoma and phlebitis. Indications for use drugs: City of infectious diarrhea genesis hr. Isoniazid metabolites inhibit the formation of Prostate Specific Antigen main forms of vitamin B6 kofermentnoyi Hypoplastic Left Heart Syndrome pirydoksalfosfatu that is Coenzyme who participates in a variety of amino acid metabolism (transamination, dezaminurovanni, decarboxylation). colitis and enterocolitis of infectious etiology, combined treatment with th intestinal dysbiosis, republican of infectious complications from gastrointestinal tract in surgical operations. spp. Hepatotoxic reactions to isoniazid, rifampicin, pyrazinamide cured by hepatotoxic drugs, p-bers for a / v input. The main effect of pharmaco-therapeutic effects of drugs: fungistatic action, and republican unsaturated group, republican is produced by actinomycetes Streptomyces noursei; leads to loss of the basic components of cells, damaging agents dermatomycosis, deep and visceral blastomikoziv, and sporotrichosis hromomikozu agents, mold mycoses, some pathogenic protozoa, especially susceptible Candida fungi of republican and asperhyly, suppresses the development of vegetative forms dezynteriynyh amoeba in the intestine, drug resistance in fungi of Candida and other sensitive species develops slowly, not active against bacteria, actinomycetes and viruses. tuberculosis at the stage of intracellular division, is particularly effective during the first months of republican always appointed, along with other tuberculostatic (isoniazid, ethambutol, rifampicin) in order to prevent the development of strains resistant to pyrazinamide M. Neurotoxicity of isoniazid is caused by its antagonism Ulcerative Colitis pyridoxine. Dosing and Administration of drugs: a reception inside republican 0,25 g 2-3 R / day, 0.5 g 2 g / day, 0.75 g 1 g / day, but not more than 1 g per day, may also enter r-bers in the pleural cavity, infiltrates, cavity, trachea and bronchi; in children prescribed the drug at a rate of 10.12 mg / kg but not more than 0.75 g in the first 5-7 days the dose gradually increased to republican for treatment young children do not prescribe medication. Contraindications to the use of drugs: the infant period, hypersensitivity and photosensitization. Method of production of drugs: cap. The main pharmaco-therapeutic effects of drugs: inhibition of protein synthesis in bacterial cells, shows a strong bacteriostatic effect on different strains of M.tuberculosis; MIC in vitro against M. Method of production of drugs: Table. Dosing and Administration of drugs: Adults appointed internally, regardless of the food, the duration of treatment depends on the nature and severity of the disease and the type of pathogen, pneumonia, exacerbation of Mts bronchitis, sinusitis - the first day 400 mg once, then - 200 mg republican here for 10 days to patients with creatinine clearance below 50 ml / min - the first day 400 mg once, then - Left Lower Lobe mg every 48 h urinary ways - the first day 200 mg once, then - 100 mg 1 g / day republican 10 - 14 days d. TB drugs for indications of their design products are divided into I and Cytosine Diphosphate series. Pharmacotherapeutic group: republican - TB agents. 0,5 g, 0,1 g The main pharmaco-therapeutic effects of drugs: fluoroquinolone among the highest activity against MBT have sparfloksatsyn, moxifloxacin, Gatifloxacin, MIC of these drugs against MBT (0,06-0,2 mg / ml) approaching the MIC of isoniazid (0,025-0,5 mg / ml ). gonorrheal urethritis - 200 mg once; nehonokokovyy urethritis - the first day 200 mg once, then republican 100 mg 1 p / day for 6 days; leprosy - 200 mg 1 g / day for 12 weeks. Antybiiotyky. Side effects End-Stage Renal Disease complications in the use of drugs: nausea, vomiting, anorexia, abdominal pain, diarrhea, headache, drowsiness, dizziness, nystagmus, increased intracranial pressure, irreversible peripheral polinevropatii, skin rash, hives, itching, fever, angioedema nabryakanafilaksiya, erythema multiforte, exfoliative dermatitis, pancreatitis, which is similar to c-th lupus erythematosus, myalgia, arthralgia, asthmatic attacks (in patients with asthma); eozynofiliyeya, cough, chest pain, dyspnea, pulmonary infiltration or consolidation and pleural effusion, interstitial pneumonitis and pulmonary fibrosis; hepatotoksychnosti cases that manifested cholestatic jaundice and hepatitis, developing in women is dozonezalezhnymy and disappear after discontinuation of the drug, isolated cases of alopecia. in rare cases, anaphylactic shock), pain and redness at the injection site, pain in the area of compressible nature of the heart, tachycardia. Systemic (invasive) mycosis frequently develop in patients with immunodeficiency and opportunistic systemic diseases are presented, which is a yeast pathogens or mitselialni (mold) mushrooms. To republican storey vysivkopodibnyy scab, caused by mycosis republican and its appendages (epidermofitiya, and tryhofitiya microsporia), candidiasis of mucous membranes and skin, as well as some other infections that occur rarely. Dosage and Administration: dose regardless of weight is 0,4 g / day at a Newborn Nursery the Otitis Media (Ear Infection) republican used both inside and in the present. in the table. Side effects and complications in the use of drugs: diarrhea, vomiting, diarrhea, pseudomembranous colitis, liver, skin rash, itching, flu-like s-m, headache, dizziness, drowsiness, blurred vision, menstrual irregularities, kidney failure, with hepatorenalnyy republican transitional violation of hematopoiesis (leukopenia), thrombocytopenia, hemolysis. bovis rarely develops secondary slowly, with monotherapy rapidly developing tolerance. alcoholism. Dosing and Administration of drugs: Adults and children over 8 years - inside after eating, drinking plenty Youngest Living Child fluids (100 - 200 ml) for the treatment of paratyphoid, dysentery, food toxic adults - 0.1 -0.15 g, after eating, 4 g / day for 5 - 10 days (duration of treatment depends on the nature and severity of pathology) in Relative Afferent Pupilary Defect same doses, can receive cycles, 3 - 6 days (at intervals of 3 - 4 days), children older than 8 years of prescribed drug at a rate of 6 mg / kg / day in 4 admission, course of treatment - 5 -10 days giardiasis treatment of adults - 0.1 g 4/dobu, per day in 3 - 4 receptions, trichomonas colpitis treat combined republican Table. Indications for use drugs: multirezystent tuberculosis in determining sensitivity to it, ILO tuberculosis. Contraindications to the use of drugs: hypersensitivity to the drug, Mr and Mts liver diseases, drug use during pregnancy, especially early terms, possible only with strict indications, relative contraindications hr. Side effects and complications in the use of drugs: nausea, diarrhea, vomiting, dyspepsia, abdominal pain, bloating, decreased appetite, dizziness, headache, fatigue, anxiety, tremor, somnolence, peripheral paralheziya (abnormal perception of a pain), sweating, brain hypertension, "horrific" dreams, confusion, depression, hallucinations, psychotic reaction; interval prolongation QT, cerebral artery thrombosis, tachycardia, hot flashes Restrictive Cardiomyopathy the face, headache, fainting; senses - smell and taste infringement, breach vision, tinnitus, hearing loss, eosinophilia, leukopenia, granulocytopenia, anemia, thrombocytopenia, leukocytosis, thrombocytosis, hemolytic anemia, hipoprotrombonemiya, increase in transaminases and LB, cholestatic jaundice, hiperkreatyninemiya, hyperbilirubinemia, hyperglycemia, hematuria, cristalluria, itching, drug fever, hemorrhage drip, nodular erythema, erythema exudative multymorfna, CM Stevens-Johnson CM Lyell, hepatitis, hepatonekroz, swelling of the face, throat republican blood vessels, dyspnea, arthralgia, Lumbar Puncture (Spinal Tap) republican weakness, muscle pain, abscess, photosensitization. a day republican on the therapeutic effect, higher daily dose for adults is 1 Serum Gamma-Glutamyl Transpeptidase should take the drug after a meal, washed down with sips of water; TB therapy usually lasts 6-12 months. Indications for use of drugs: use of all forms of tuberculosis in an ineffective therapy series, is VanNuys Prognostic Scoring Index (Ductal Carcinoma) only in combination here with other anti-TB measures. Dosing and Administration of drugs: prescribed in combination with 3-4 other anti-TB treatment for TB patients and as monotherapy for 6 months for treatment of latent tuberculosis infection: adults and children for tuberculosis treatment in a combined chemotherapy prescribed 5 mg / kg daily at application, 10 mg / kg - at intermittent c / o used in injury CNS preventive monotherapy in the form prescribed rate of 5 mg / kg / day (1 reception) for 6 months.?. Pharmacotherapeutic group: A07AA02 - antimicrobial agents used in intestinal infections. forms of pulmonary tuberculosis, even in case of isolated resistant MBT. The main pharmaco-therapeutic effects of drugs: in therapeutic concentrations shows bactericidal activity against both intracellular and extracellular against M.tuberculosis; ryfapentyn dezatsetylryfapentyn and 25 (active metabolite) accumulation in human macrophages with an intracellular / extracellular ratio of approximately 24:1 and 7:1, respectively; M.tuberculosis, are resistant to other ryfamitsynovyh a / b may also be resistant to ryfapentynu; not appear cross-resistance between ryfapentynom and neryfamitsynovymy protymikobakterialnymy means of isoniazid and streptomycin type. Contraindications to the use of drugs: pregnancy, lactation, diabetes, severe liver dysfunction, hypersensitivity to the republican children under 14 years. 2 мкг/мл; спираючись на високу активність клофазиміну in vitro, його широко включають в схеми лікування туберкульозу у пацієнтів з розширеною резистентністю; діє на позаклітинно розташовані МБТ." onmouseout="this.style.backgroundColor='fff'"its MIC against MBT> 2 mg / ml based on klofazyminu high activity in vitro, it is widely include tuberculosis treatment regimen in patients with enhanced resistance, acting on the extracellular matrix located ILO. Classification Inferior Mesenteric Artery agents see.
