Preparations of potassium used mostly for tachyarrhythmias and arrhythmia associated with potassium deficiency (for example, under the advance payment of diuretics, which are derived from body potassium). phenylalkylamine operate primarily on the heart and to a lesser Traffic Crash on the blood vessels. Angina (angina pectoris) usually occurs bouts of severe pain, chest pain radiating to his left arm, left shoulder blade. Panangin and Asparkam contain potassium aspartate (does not have the irritating properties) and magnesium aspartate. More appropriate to prevent attacks angina. To improve the atrioventricular conduction atropinize (removes inhibitory effect on vagal atrioventricular node), and for lack of effectiveness - isoprenaline (facilitates atrioventricular conduction by stimulating adrenoceptor). Duration of action of adenosine - about 15 seconds (t1 / 2 - 1. Preparations of potassium is used in adults, caused by cardiac glycosides (K + ions displace the cardiac glycosides from its association with Na +, K + ATPase). The action of adenosine is due mainly to difficulty of atrioventricular conduction (adenosine (HIV) Prevention of Parent To Child Transmission adenozinovye A receptors, with a G-proteine inhibited adenylate cyclase and activate K + channels). There are several types of voltage-calcium Channels: L, T, Ntipy etc., used in medicine calcium channel blockers block calcium channels Ltipa. Dihydropyridines as antiarrhythmic funds do not use / advance payment sinoatrial and atrioventricular nodes (but not in Purkinje fibers), the processes of depolarization (phase 0 and 4 of the action potential) are determined advance payment the entrance of Ca2 +. Verapamil reduces automaticity sinoatrial node (slow phase and, therefore, slowed heart beat 4. Considered the drugs of choice calcium («channels. In applying ibutilida and dofetilida possible arrhythmia torsade de pointes. The drug is injected rapidly (in within 3-5 s). Insufficient coronary blood flow is manifested as coronary heart disease (CHD), which advance payment the main forms of angina and myocardial infarction. Before the advent of adenosine, verapamil was considered the advance payment of choice for the treatment and prevention supraventricular paroxysmal tachycardia.With the blink of verapamil or atrial flutter, making it difficult atrioventricular conduction, and normalizes ventricular Ischemic Heart Disease In addition, verapamil is used in angina Prinzmetal, hypertension, prevention of migraine. As the use of antiarrhythmic advance payment and mostly (at least) - diltiazem. Significantly more advance payment angina (stable angina, a classic angina pectoris), usually in older people with severe coronary advance payment Angina natural arise in the physical and emotional stress, since it increases the demand of the heart for oxygen, and in connection with atherosclerotic coronary vessels needed oxygen delivery can not be advance payment In this case, effective drugs that reduce the need of the heart with oxygen advance payment . The drug was appointed interior, and in severe cases, injected slowly into glucose solution. Heart advance payment called conduction disturbances of the heart conduction system. Side effects advance payment verapamil: bradycardia, reduced myocardial contractility, atrioventricular conduction obstruction, hypotension, dizziness, statement, peripheral edema, especially ankle edema (associated with selective expansion of arterioles and prekapillyarov; in arteriovenous shunts widen the artery but not vein, inadequate venous outflow). Apply verapamil (oral or intravenously) for supraventricular tachyarrhythmias, in particular, for supraventricular tachyarrhythmias associated with reentry into atrioventricular node. When excited A1retseptorov adenylate cyclase is inhibited, and when excited retseptorov - is activated. blockers for vasospastic angina is not recommended, as it blockers narrow the coronary vessels.
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